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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
15.15
Human Site:
T523
Identified Species:
23.81
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
T523
L
Y
L
P
Q
E
P
T
S
E
E
T
P
R
T
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
T520
L
Y
L
P
Q
E
P
T
S
E
E
T
P
R
T
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
T636
L
Y
L
P
Q
E
P
T
F
E
E
T
P
R
T
Dog
Lupus familis
XP_548434
951
104664
T585
L
Y
L
P
R
E
P
T
S
E
E
I
P
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
P512
P
R
L
Y
L
Q
E
P
A
P
G
T
P
C
T
Rat
Rattus norvegicus
O08874
985
112050
E587
P
R
A
S
S
L
G
E
I
D
D
S
S
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
V621
L
F
L
P
L
E
P
V
A
G
D
S
P
C
T
Chicken
Gallus gallus
XP_422357
1013
114806
H659
I
C
E
S
D
V
P
H
S
D
I
K
Y
T
N
Frog
Xenopus laevis
Q7ZX15
486
56292
E191
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
E575
A
Q
N
P
S
A
D
E
S
L
S
G
T
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
I339
K
V
L
K
K
D
A
I
I
Q
D
D
D
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
G399
V
M
L
A
E
R
K
G
T
D
E
V
Y
A
I
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
L412
G
V
E
V
Q
D
A
L
S
S
F
D
F
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
Y642
F
I
D
E
N
E
A
Y
L
N
F
T
E
G
A
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T769
M
Y
Q
Q
N
P
Q
T
P
I
S
K
P
Q
P
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
93.3
86.6
N.A.
26.6
0
N.A.
46.6
13.3
0
13.3
N.A.
6.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
40
20
N.A.
73.3
26.6
0
13.3
N.A.
33.3
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
7
0
7
20
0
14
0
0
7
0
7
14
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
14
0
% C
% Asp:
0
0
7
0
7
14
7
0
0
20
20
14
7
7
7
% D
% Glu:
0
0
14
7
7
40
7
20
0
27
34
0
7
7
7
% E
% Phe:
7
7
0
0
0
0
0
0
7
0
14
0
7
0
0
% F
% Gly:
7
0
0
0
0
0
7
7
0
7
7
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
0
0
7
14
14
14
7
0
0
7
% I
% Lys:
7
0
7
7
7
0
14
0
0
0
0
14
7
0
0
% K
% Leu:
34
0
54
0
20
7
0
7
7
7
0
0
0
7
7
% L
% Met:
7
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
14
0
0
0
0
7
0
0
0
0
14
% N
% Pro:
14
0
0
40
0
7
40
7
7
7
0
0
47
7
7
% P
% Gln:
0
7
7
7
27
7
7
0
0
7
0
0
0
7
0
% Q
% Arg:
0
14
0
0
7
14
0
0
0
0
0
0
0
27
0
% R
% Ser:
0
0
0
14
14
0
0
0
40
7
14
14
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
7
0
0
34
7
7
40
% T
% Val:
7
14
0
7
0
7
0
7
7
0
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
0
7
0
0
0
7
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _